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17 stars written in C
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RNA-seq aligner

C 2,096 542 Updated Mar 18, 2025

De novo assembler for single molecule sequencing reads using repeat graphs

C 884 173 Updated May 2, 2025

HMMER: biological sequence analysis using profile HMMs

C 391 85 Updated Sep 26, 2025

Align proteins to genomes with splicing and frameshift

C 388 21 Updated Sep 20, 2025

Inference of ploidy and heterozygosity structure using whole genome sequencing data

C 289 28 Updated Dec 10, 2025

haplotypic duplication identification tool

C 270 24 Updated Oct 30, 2025

abPOA: an SIMD-based C library for fast partial order alignment using adaptive band

C 134 20 Updated Oct 26, 2025
C 121 12 Updated Nov 15, 2025

A EXPERIMENTAL fork of minimap2 optimized for assembly-to-reference alignment

C 87 4 Updated Apr 8, 2021

BAMscale is a one-step tool for either 1) quantifying and normalizing the coverage of peaks or 2) generated scaled BigWig files for easy visualization of commonly used DNA-seq capture based methods.

C 72 17 Updated Dec 4, 2024

Evaluate variant calls and its combination with k-mer multiplicity

C 67 7 Updated Dec 2, 2022

PoSeiDon: positive selection detection and recombination analysis pipeline

C 39 9 Updated Sep 22, 2025

Pipeline to detect PAVs (presence/absence variations) in genome comparison using whole genome alignment.

C 29 7 Updated Mar 5, 2018

Hapo-G is a tool that aims to improve the quality of genome assemblies by polishing the consensus with accurate reads.

C 26 2 Updated Oct 24, 2025

R Interface to CoreArray Genomic Data Structure (GDS) Files (Development version only)

C 20 4 Updated Dec 17, 2025

Co-phylog: an assembly-free phylogenomic approach for closely related organisms

C 4 1 Updated Aug 11, 2023