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5 stars written in Perl
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These are policy-driven snapshot management and replication tools which use OpenZFS for underlying next-gen storage. (Btrfs support plans are shelved unless and until btrfs becomes reliable.)

Perl 3,701 340 Updated Feb 18, 2026

Trinity RNA-Seq de novo transcriptome assembly

Perl 885 320 Updated Feb 7, 2025

A software for the multispecies design of CRISPR/Cas9 libraries

Perl 36 16 Updated Oct 7, 2022

Differential analysis for ChIP-seq with biological replicates

Perl 35 17 Updated Jan 5, 2022

Allele-specific Binding from Chip-seq

Perl 6 9 Updated Jun 12, 2015