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105 stars written in Python
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What the f*ck Python? 😱

Python 36,913 2,664 Updated Jan 13, 2026

⚡ A Fast, Extensible Progress Bar for Python and CLI

Python 31,059 1,441 Updated Feb 14, 2026

Python logging made (stupidly) simple

Python 23,726 775 Updated Mar 21, 2026

Turn (almost) any Python command line program into a full GUI application with one line

Python 22,028 1,044 Updated Mar 23, 2026

Memray is a memory profiler for Python

Python 14,959 435 Updated Mar 13, 2026

Pyodide is a Python distribution for the browser and Node.js based on WebAssembly

Python 14,447 1,003 Updated Mar 20, 2026

Gel supercharges Postgres with a modern data model, graph queries, Auth & AI solutions, and much more.

Python 14,083 445 Updated Dec 24, 2025

An open source multi-tool for exploring and publishing data

Python 10,864 815 Updated Mar 18, 2026

A set of tools to keep your pinned Python dependencies fresh.

Python 7,997 653 Updated Mar 20, 2026

Evolutionary Scale Modeling (esm): Pretrained language models for proteins

Python 4,008 779 Updated Feb 7, 2024

A terminal application to view, tail, merge, and search log files (plus JSONL).

Python 3,890 88 Updated Aug 5, 2024

Official repository for the Boltz biomolecular interaction models

Python 3,855 779 Updated Mar 23, 2026

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

Python 3,662 774 Updated Mar 19, 2026

napari: a fast, interactive, multi-dimensional image viewer for python

Python 2,610 478 Updated Mar 23, 2026

Turn repositories into Jupyter-enabled Docker images

Python 1,715 384 Updated Mar 13, 2026

Implementation of Alphafold 3 from Google Deepmind in Pytorch

Python 1,623 215 Updated Sep 18, 2025

A powerful and flexible machine learning platform for drug discovery

Python 1,574 219 Updated Aug 12, 2024

A Data Streaming Library for Efficient Neural Network Training

Python 1,478 188 Updated Feb 2, 2026

Implementation of DiffDock: Diffusion Steps, Twists, and Turns for Molecular Docking

Python 1,467 349 Updated May 2, 2025

Toolbox for molecular animations in Blender, powered by Geometry Nodes.

Python 1,222 116 Updated Mar 22, 2026

In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more

Python 786 298 Updated Feb 17, 2024

Working with molecular structures in pandas DataFrames

Python 752 116 Updated Aug 1, 2024

Python Client and Toolkit for DataFrames, Big Data, Machine Learning and ETL in Elasticsearch

Python 694 107 Updated Mar 20, 2026

👁️ Python library to plot DNA sequence features (e.g. from Genbank files)

Python 683 104 Updated Jul 2, 2025

Incubator for useful bioinformatics code, primarily in Python and R

Python 645 244 Updated Feb 5, 2025

Gene cluster comparison figure generator

Python 638 77 Updated Dec 22, 2025

Rapid & standardized annotation of bacterial genomes, MAGs & plasmids

Python 614 76 Updated Feb 18, 2026

A tool to find sequencing data and metadata from public databases.

Python 597 48 Updated Aug 13, 2024

Open-source bioinformatics components for Dash

Python 571 193 Updated Mar 24, 2025

Plot structural variant signals from many BAMs and CRAMs

Python 562 72 Updated Jul 13, 2024
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