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107 stars written in Python
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Animation engine for explanatory math videos

Python 85,661 7,197 Updated Mar 26, 2026

openpilot is an operating system for robotics. Currently, it upgrades the driver assistance system on 300+ supported cars.

Python 60,461 10,770 Updated Mar 31, 2026

You like pytorch? You like micrograd? You love tinygrad! ❤️

Python 32,026 4,012 Updated Mar 31, 2026

Open source code for AlphaFold 2.

Python 14,418 2,592 Updated Mar 13, 2026

Uniform Manifold Approximation and Projection

Python 8,132 860 Updated Mar 23, 2026

AlphaFold 3 inference pipeline.

Python 7,785 1,164 Updated Mar 31, 2026

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

Python 3,668 777 Updated Mar 19, 2026

a Python API for your car

Python 3,036 1,854 Updated Mar 31, 2026

Low bandwidth DoS tool. Slowloris rewrite in Python.

Python 2,768 731 Updated Jun 1, 2024

This is the development home of the workflow management system Snakemake. For general information, see

Python 2,737 634 Updated Mar 31, 2026

Nice-looking lightweight console ASCII line charts ╭┈╯ for NodeJS, browsers and terminal, no dependencies

Python 2,068 100 Updated Mar 27, 2026

Access a database of word frequencies, in various natural languages.

Python 1,640 110 Updated Jan 4, 2025

Non-Linear Least Squares Minimization, with flexible Parameter settings, based on scipy.optimize, and with many additional classes and methods for curve fitting.

Python 1,208 287 Updated Mar 22, 2026

Scripts to download genomes from the NCBI FTP servers

Python 1,069 177 Updated Jul 28, 2025

Fast genome-wide functional annotation through orthology assignment

Python 715 119 Updated Mar 24, 2026

Rapid & standardized annotation of bacterial genomes, MAGs & plasmids

Python 617 76 Updated Feb 18, 2026

GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.

Python 587 97 Updated Feb 21, 2026

COBRApy is a package for constraint-based modeling of metabolic networks.

Python 554 234 Updated Mar 26, 2026

Software package for assigning SARS-CoV-2 genome sequences to global lineages.

Python 452 109 Updated Mar 30, 2026

A PyTorch Basecaller for Oxford Nanopore Reads

Python 430 136 Updated Feb 20, 2026

Assess the quality of microbial genomes recovered from isolates, single cells, and metagenomes

Python 405 77 Updated Mar 2, 2026

MetaPhlAn is a computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data

Python 397 92 Updated Mar 16, 2026

An updated pipeline for pangenome investigation

Python 352 38 Updated Jan 15, 2026

A tool for generating consensus long-read assemblies for bacterial genomes

Python 341 32 Updated Sep 11, 2025

Distilled and Refined Annotation of Metabolism: A tool for the annotation and curation of function for microbial and viral genomes

Python 326 59 Updated Mar 30, 2026

Variational autoencoder for metagenomic binning

Python 319 50 Updated Feb 23, 2026

Build a partitioned pangenome graph from microbial genomes

Python 296 31 Updated Mar 30, 2026

customizable pipeline to identify viral sequences from (meta)genomic data

Python 284 33 Updated Nov 28, 2024

💎 An easy-to-use workflow for generating context specific genome-scale metabolic models and predicting metabolic interactions within microbial communities directly from metagenomic data

Python 257 46 Updated Jul 27, 2024
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