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@staphopia @Read-Lab-Confederation @conda-forge @bioconda @MetaSUB @bactopia

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24 stars written in C
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Command-line JSON processor

C 34,588 1,768 Updated Apr 26, 2026

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,165 461 Updated Apr 25, 2026

Tools (written in C using htslib) for manipulating next-generation sequencing data

C 1,889 610 Updated Apr 29, 2026

Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment)

C 1,731 579 Updated Mar 22, 2025

Toolkit for processing sequences in FASTA/Q formats

C 1,539 328 Updated Jun 1, 2025

bedtools - the swiss army knife for genome arithmetic

C 1,030 295 Updated Mar 11, 2025

De novo assembler for single molecule sequencing reads using repeat graphs

C 921 179 Updated Apr 3, 2026

This is the official development repository for BCFtools. See installation instructions and other documentation here http://samtools.github.io/bcftools/howtos/install.html

C 861 269 Updated Apr 7, 2026

Prodigal Gene Prediction Software

C 538 94 Updated Jan 23, 2024

Align proteins to genomes with splicing and frameshift

C 401 22 Updated Jan 5, 2026

Fast taxonomic classification of metagenomic sequencing reads using a protein reference database

C 302 70 Updated Apr 25, 2025

Short read de novo assembler using de Bruijn graphs, as published in: D.R. Zerbino and E. Birney. 2008. Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Research, 1…

C 298 100 Updated Oct 13, 2025

Finds SNP sites from a multi-FASTA alignment file

C 278 49 Updated Dec 16, 2020

Fast and accurately polish the genome generated by long reads.

C 243 30 Updated Jan 9, 2025

Robinhood Policy Engine : a versatile tool to monitor filesystem contents and schedule actions on filesystem entries.

C 216 64 Updated Jan 29, 2026

Constructing a pangenome gene graph

C 206 14 Updated Aug 11, 2025

A tool set for short variant discovery in genetic sequence data.

C 205 5 Updated May 4, 2021

Simple oligo analysis and primer design

C 190 47 Updated Jan 26, 2026

A genomic k-mer counter (and sequence utility) with nice features.

C 167 15 Updated Jul 4, 2025

Pairwise SNP distance matrix from a FASTA sequence alignment

C 154 32 Updated Dec 31, 2025

De novo genome assembly and multisample variant calling

C 112 24 Updated Mar 28, 2019

a python package for finding tandem repeats from genomic sequences

C 31 Updated Mar 19, 2025

Calculate confidence scores from Kraken2 output

C 25 7 Updated Feb 18, 2024

Rapidly extract a flexible bacterial core genome alignment

C 2 Updated Oct 7, 2025