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Run your GitHub Actions locally 🚀

Go 67,644 1,805 Updated Dec 1, 2025

The uncompromising Python code formatter

Python 41,227 2,690 Updated Dec 12, 2025

The official Python library for the OpenAI API

Python 29,506 4,471 Updated Dec 17, 2025

Python composable command line interface toolkit

Python 17,061 1,511 Updated Dec 10, 2025

✨ Finder Toolbar app for macOS to open the current directory in Terminal, iTerm, Hyper or Alacritty.

Swift 6,555 265 Updated Jan 18, 2025

Package management made easy

Rust 5,914 389 Updated Dec 17, 2025

FUSE filesystem over Google Drive

OCaml 5,834 362 Updated Oct 26, 2025

A simple and efficient tool to parallelize Pandas operations on all available CPUs

Python 3,802 212 Updated Jul 9, 2024

A DSL for data-driven computational pipelines

Groovy 3,239 752 Updated Dec 17, 2025

This is the development home of the workflow management system Snakemake. For general information, see

Python 2,662 617 Updated Dec 17, 2025

R toolkit for single cell genomics

R 2,590 976 Updated Dec 17, 2025

YouTube script to add the new Ads list for Pi-hole

Shell 2,551 260 Updated Aug 5, 2024

A 21 century R console

Python 2,223 85 Updated May 15, 2025
Python 2,179 267 Updated Nov 24, 2025

RNA-seq aligner

C 2,095 542 Updated Mar 18, 2025

A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,092 448 Updated Dec 12, 2025

Tool for creating snapshots and remote backups of btrfs subvolumes

Perl 2,000 134 Updated Nov 29, 2025

Official code repository for GATK versions 4 and up

Java 1,892 622 Updated Dec 17, 2025

Apptainer: Application containers for Linux

Go 1,663 164 Updated Dec 16, 2025

Python and tab completion, better together.

Python 1,530 142 Updated Oct 20, 2025

Toolkit for processing sequences in FASTA/Q formats

C 1,516 327 Updated Jun 1, 2025

A set of command line tools (in Java) for manipulating high-throughput sequencing (HTS) data and formats such as SAM/BAM/CRAM and VCF.

Java 1,036 382 Updated Nov 13, 2025

🎨🎨🎨 Collection of most color palettes in a single R package

R 1,018 52 Updated Jun 24, 2024

bedtools - the swiss army knife for genome arithmetic

C 1,015 296 Updated Mar 11, 2025

The complete sequence of a human genome

1,007 100 Updated Jul 14, 2025

Python interface to Graphviz's Dot language

Python 976 169 Updated Dec 3, 2025

Multi-featured system monitor

Python 941 95 Updated Oct 31, 2023

🎨 Visualisation toolbox for beautiful and publication-ready figures

R 936 46 Updated Dec 1, 2025

dplyr-style piping operations for pandas dataframes

Python 898 102 Updated May 8, 2022

Trinity RNA-Seq de novo transcriptome assembly

Perl 879 321 Updated Feb 7, 2025
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