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52 results for source starred repositories written in C++
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An ultra-fast all-in-one FASTQ preprocessor (QC/adapters/trimming/filtering/splitting/merging...)

C++ 2,212 355 Updated Oct 14, 2025

tools for working with genome variation graphs

C++ 1,254 209 Updated Nov 6, 2025

Versatile open-source tool for microbiome analysis

C++ 722 129 Updated Oct 24, 2025

Mummer alignment tool

C++ 533 111 Updated Feb 4, 2025

Transcript assembly and quantification for RNA-Seq

C++ 472 85 Updated Oct 22, 2025

GFF/GTF utility providing format conversions, region filtering, FASTA sequence extraction and more

C++ 443 42 Updated Dec 26, 2024

Fast Whole-Genome Similarity (ANI) Estimation

C++ 435 69 Updated Jul 24, 2025

A tool for automated alignment trimming in large-scale phylogenetic analyses. Development version: 2.0

C++ 233 47 Updated Nov 6, 2025

Accurate Species Tree EstimatoR: a family of optimation algorithms for species tree inference (including ASTRAL & CASTER)

C++ 209 16 Updated Nov 6, 2025

base-accurate DNA sequence alignments using WFA and mashmap3

C++ 206 25 Updated Sep 22, 2025

Fast alignment and preprocessing of chromatin profiles

C++ 206 26 Updated Sep 20, 2025

Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism and whole-genome duplication variation

C++ 178 20 Updated Oct 15, 2025

Hierarchical Alignment Format

C++ 173 39 Updated Sep 9, 2025

A fast whole-genome aligner based on de Bruijn graphs

C++ 153 19 Updated Jul 6, 2025

Integrate DNA-seq and RNA-seq data to identify mutations that are associated with regulatory effects on gene expression.

C++ 132 29 Updated Aug 21, 2024

phylogenetics tools for linux (and other mostly posix compliant) computers

C++ 122 17 Updated Jan 17, 2025

Analyze changes in gene family size and provide a statistical foundation for evolutionary inferences.

C++ 117 37 Updated Apr 7, 2021

A single fast and exhaustive tool for summary statistics and simultaneous *fa* (fasta, fastq, gfa [.gz]) genome assembly file manipulation.

C++ 114 11 Updated Jun 3, 2025

MECAT: an ultra-fast mapping, error correction and de novo assembly tool for single-molecule sequencing reads

C++ 111 26 Updated Oct 2, 2020

A pipeline used to identify different modes of duplicated gene pairs

C++ 109 34 Updated Jul 22, 2025

Scallop is a reference-based transcriptome assembler for RNA-seq

C++ 91 17 Updated Apr 30, 2021

A program to call variants from genome alignment

C++ 81 18 Updated Apr 29, 2025

The LACHESIS software, as described in Nature Biotechnology (http://dx.doi.org/10.1038/nbt.2727)

C++ 80 30 Updated Oct 12, 2018

A genome assembler that reduces the computational time of human genome assembly from 400,000 CPU hours to 2,000 CPU hours, utilizing long erroneous 3GS sequencing reads and short accurate NGS seque…

C++ 67 27 Updated Jul 23, 2020

calling SVs from Blasr contig level alignments

C++ 54 24 Updated Mar 9, 2018

Find and visualize rearrangements in DNA sequences

C++ 54 13 Updated Apr 14, 2024

OpenGL Powered Pretext Contact Map Viewer

C++ 48 9 Updated Nov 3, 2025

FFT cross-correlation based synteny aligner, (re)designed to make full use of parallel computing

C++ 43 13 Updated Dec 21, 2021

Splice junction analysis and filtering from BAM files

C++ 42 9 Updated Mar 31, 2022

Population-wide Deletion Calling

C++ 35 2 Updated Apr 16, 2025
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