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68 results for source starred repositories written in C
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A versatile pairwise aligner for genomic and spliced nucleotide sequences

C 2,066 445 Updated Oct 5, 2025

MMseqs2: ultra fast and sensitive search and clustering suite

C 1,872 248 Updated Oct 21, 2025

Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment)

C 1,671 564 Updated Mar 22, 2025

Toolkit for processing sequences in FASTA/Q formats

C 1,507 326 Updated Jun 1, 2025

De novo assembler for single molecule sequencing reads using repeat graphs

C 878 171 Updated May 2, 2025

Near-optimal RNA-Seq quantification

C 707 177 Updated Apr 9, 2025

BWK awk modified for biological data

C 631 116 Updated Aug 11, 2022

Official home of genome aligner based upon notion of Cactus graphs

C 620 123 Updated Nov 5, 2025

Redbean: A fuzzy Bruijn graph approach to long noisy reads assembly

C 529 93 Updated Sep 27, 2023

Prodigal Gene Prediction Software

C 513 91 Updated Jan 23, 2024

Fast and accurate de novo assembler for long reads

C 395 54 Updated May 10, 2024

HMMER: biological sequence analysis using profile HMMs

C 387 84 Updated Sep 26, 2025

Align proteins to genomes with splicing and frameshift

C 382 21 Updated Sep 20, 2025

Long read / genome alignment software

C 305 29 Updated Nov 5, 2024

haplotypic duplication identification tool

C 265 24 Updated Oct 30, 2025

UCSC Genome Browser source. "beta" is released version / "master" is testing.

C 247 97 Updated Nov 6, 2025

Tools for manipulating sequence graphs in the GFA and rGFA formats

C 238 21 Updated Aug 15, 2024

Fast and accurately polish the genome generated by long reads.

C 234 29 Updated Jan 9, 2025

Program for aligning DNA sequences, a pairwise aligner.

C 230 39 Updated Jun 16, 2025

Detecting sites of genomic enrichment

C 195 29 Updated May 8, 2023

UCSC command line bioinformatic utilities

C 186 95 Updated Jul 31, 2024

Implementation of the Pairwise Sequentially Markovian Coalescent (PSMC) model

C 174 59 Updated Nov 4, 2025

Nanopore data assembler

C 161 23 Updated Mar 27, 2022

Yet another k-mer analyzer

C 151 10 Updated Oct 8, 2025

Ultra-fast de novo assembler using long noisy reads

C 135 31 Updated Feb 24, 2021

TAD calling, phase imputation, 3D modeling and more for diploid single-cell Hi-C (Dip-C) and general Hi-C

C 113 12 Updated Feb 4, 2021

Bioinformatics tools for dealing with Multiple Alignment Format (MAF) files.

C 109 32 Updated Jun 17, 2022

The MARVEL assembler

C 79 23 Updated Jul 7, 2023

PHAST

C 76 27 Updated Nov 6, 2025
C 76 85 Updated Apr 23, 2020
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