RUFUS k-mer based genomic variant detection

Convert SAM files to RAM (ROOT Alignment/Map) files.

Merge and compare structural variants across callers, samples, and platforms. Standardizes BND-heavy output from GRIDSS, SvABA, Sniffles, and more.

Fast, flexible and extensible genome browser.

A native port of Lotus 1-2-3 to Linux.

ROSE: RANK ORDERING OF SUPER-ENHANCERS

Fully documented source code for the classic game The Sentinel on the BBC Micro

Native Rust reimplementation of GATK 4.6.2.0, byte-identical target. Work in progress. Not the official GATK.

Spiritual successor to picard for sequencing qc

Modern ggplot2 visualizations for GWAS summary statistics

Genome modeling and design across all domains of life

fastrgz is a fast and efficient gzip compression tool for sequencing data (FASTQ)

The CSV magician

An extensible and performant aligner and read mapper

A k-mer search engine for all Sequence Read Archive public accessions

Interactive remake of Sparks's 1931 Histomap: 4,000 years of world history as a population stream graph (Cliopatria x HYDE), with civilizational coloring, geographic focus, and data-driven event an…

Successor of bwa-mem for short-read alignment

ChIP-Atlas: Browse and analyze all public ChIP/DNase-seq data on your browser

Minimal CSS Framework for semantic HTML

Fast, accurate and simple to use command line tool for variant detection in NGS data.

Suite of heritability and genetic correlation estimation tools for exome-sequencing data

quick qc on long-read alignment files. Show read-length and depth distributions

Rust FFI crate for bwa-mem3 with packed-BAM output and caller-owned parallelism

markdup-wea: Rust rewrite of Picard MarkDuplicates — 3.26x faster, 54x less RAM, byte-identical output on 8 ENCODE RNA-seq samples vs Picard 3.4.0. Plus nf-core/rnaseq Picard memory-tuning proposal.

fastVEP: High-performance Variant Effect Predictor in Rust