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307 stars written in Python
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Snakemake workflow for highly parallel variant calling designed for ease-of-use in non-model organisms.

Python 83 31 Updated Aug 26, 2025

Topology weighting by iterative sampling of sub-trees

Python 82 18 Updated Jan 5, 2025

a multiple sequence alignment-trimming algorithm for accurate phylogenomic inference

Python 80 5 Updated Oct 17, 2025

Long-reads Gap-free Chromosome-scale Assembler

Python 79 17 Updated Mar 21, 2023

Best practices and workflow for genome annotation

Python 78 14 Updated Apr 14, 2025

Algorithm For Gene Order Reconstruction in Ancestors

Python 77 16 Updated Aug 16, 2025

A fast and efficient tool for converting chromatin interaction data between genome assemblies

Python 75 5 Updated Jul 22, 2025

a UNIX shell toolkit for processing and analyzing multiple sequence alignments and phylogenies

Python 75 8 Updated Sep 25, 2025

A computation framework for genome-wide detection of enhancer-hijacking events from chromatin interaction data in re-arranged genomes

Python 73 17 Updated Oct 21, 2023

convert various features into a GFF-like file for use in genome browsers

Python 72 27 Updated Jul 10, 2025

Tools to analyze Dip-C (or other 3C/Hi-C) data

Python 72 20 Updated Nov 14, 2024

A Snakemake workflow and MrBiomics module for performing genomic region set and gene set enrichment analyses using LOLA, GREAT, GSEApy, pycisTarget and RcisTarget.

Python 70 3 Updated Sep 24, 2025

An accessible and flexible tool for fitting demographic models with dadi using custom or published models (available here), conducting goodness of fit tests, and plotting.

Python 67 33 Updated Apr 25, 2024

A tool to extract and visualize the results of CAFE (Computational Analysis of gene Family Evolution)

Python 63 17 Updated Sep 5, 2019

An efficient way to convert gff3 annotation files into EMBL format ready to submit.

Python 63 15 Updated Jul 31, 2025
Python 60 38 Updated Mar 14, 2024

Protein hint generation pipeline for gene finding in eukaryotic genomes

Python 60 13 Updated Oct 27, 2023

A modular, containerized pipeline for ATAC-seq data processing

Python 60 16 Updated Sep 23, 2025

Portable solution to generate genome alignment chains using lastz

Python 59 12 Updated Sep 23, 2025

Structural variant caller

Python 55 6 Updated Dec 8, 2021

create, manage, and upload track hubs for use in the UCSC genome browser

Python 54 20 Updated Apr 20, 2024

My bioinfo toolbox

Python 50 31 Updated Feb 6, 2025
Python 49 6 Updated Dec 29, 2022
Python 49 7 Updated Jun 25, 2024

TSEBRA: Transcript Selector for BRAKER

Python 48 4 Updated Nov 13, 2024

TADtool is an interactive tool for the identification of meaningful parameters in TAD-calling algorithms for Hi-C data.

Python 48 13 Updated Nov 16, 2022

Plant genome assembly and annotation pipeline using snakemake

Python 48 12 Updated May 14, 2025

scripts for the project of seven thaliana genomes assembly

Python 42 19 Updated May 22, 2021