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307 stars written in Python
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Open source code for AlphaFold 2.

Python 13,930 2,501 Updated Oct 31, 2025

Trainable, memory-efficient, and GPU-friendly PyTorch reproduction of AlphaFold 2

Python 3,185 636 Updated Sep 15, 2025

Single-cell analysis in Python. Scales to >100M cells.

Python 2,246 675 Updated Nov 4, 2025

RNAseq analysis notes from Ming Tang

Python 1,050 320 Updated Nov 15, 2021

Python library to facilitate genome assembly, annotation, and comparative genomics

Python 869 194 Updated Aug 24, 2025

python module to plot beautiful and highly customizable genome browser tracks

Python 846 125 Updated Jul 10, 2024

ChIP-seq analysis notes from Ming Tang

Python 827 309 Updated Aug 5, 2024

Phylogenetic orthology inference for comparative genomics

Python 809 199 Updated Jul 15, 2025

Tools to process and analyze deep sequencing data.

Python 741 219 Updated Jul 23, 2025

Fast genome-wide functional annotation through orthology assignment

Python 668 112 Updated Jun 18, 2025

Gene cluster comparison figure generator

Python 622 74 Updated Nov 25, 2024

Bioinformatics code libraries and scripts

Python 550 253 Updated Jul 22, 2025

Tools for fast and flexible genome assembly scaffolding and improvement

Python 536 55 Updated Feb 14, 2024

An accurate GFF3/GTF lift over pipeline

Python 512 58 Updated Aug 1, 2023

ENCODE ATAC-seq pipeline

Python 434 172 Updated Jul 18, 2024

General tools for genomic analyses.

Python 376 98 Updated Feb 28, 2025

Telomere-to-telomere assembly of accurate long reads (PacBio HiFi, Oxford Nanopore Duplex, HERRO corrected Oxford Nanopore Simplex) and Oxford Nanopore ultra-long reads.

Python 366 33 Updated Sep 29, 2025

Eukaryotic Genome Annotation Pipeline

Python 366 88 Updated Jul 6, 2025

Tool to plot synteny and structural rearrangements between genomes

Python 328 30 Updated Apr 7, 2025

Python wrapper -- and more -- for BEDTools (bioinformatics tools for "genome arithmetic")

Python 327 107 Updated Mar 16, 2025

Convert SNPs in VCF format to PHYLIP, NEXUS, binary NEXUS, or FASTA alignments for phylogenetic analysis

Python 320 88 Updated Jul 7, 2023

GFF and GTF file manipulation and interconversion

Python 308 80 Updated Apr 13, 2024

ENCODE ChIP-seq pipeline

Python 275 120 Updated Feb 15, 2024

Long read based human genomic structural variation detection with cuteSV

Python 274 38 Updated Sep 30, 2025

An overview of all nanopack tools

Python 272 18 Updated Jun 2, 2023

This Snakemake pipeline implements the GATK best-practices workflow

Python 260 147 Updated Jun 8, 2023

HiCExplorer is a powerful and easy to use set of tools to process, normalize and visualize Hi-C data.

Python 256 74 Updated Jul 17, 2025

Cell type specific enhancer-gene predictions using ABC model (Fulco, Nasser et al, Nature Genetics 2019)

Python 239 73 Updated Jun 27, 2025

HapHiC: a fast, reference-independent, allele-aware scaffolding tool based on Hi-C data

Python 238 13 Updated Oct 30, 2025

FALCON: experimental PacBio diploid assembler -- Out-of-date -- Please use a binary release: https://github.com/PacificBiosciences/FALCON_unzip/wiki/Binaries

Python 205 102 Updated Mar 4, 2022
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