호모 사피엔스 종의 단백질 코드 유전자
ETV1 식별자 에일리어스 ETV1 외부 ID OMIM : 600541 MGI : 99254 HomoloGene : 3636 GenCard: ETV1 유전자 존재론 분자 함수 GO:0001131, GO:000115, GO:0001130, GO:0001204 DNA결합전사인자액티비티 GO:0000980 RNA중합효소II 시스조절영역배열특이적 DNA결합 DNA결합 배열특이적 DNA결합 GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA결합전사활성화제, RNA중합효소II 특이적 GO:0001948 단백질 결합 GO:0001200, GO:0001133, GO:0001201 DNA결합전사인자활성, RNA중합효소II 특이적 셀룰러 컴포넌트 생물학적 과정 출처: 아미고 / QuickGO
맞춤법 종. 인간 마우스 엔트레즈 앙상블 유니프로트 RefSeq(mRNA) RefSeq(단백질) 장소(UCSC) Chr 7: 13.89 ~13.99 Mb Chr 12: 38.83 ~38.92 Mb PubMed 검색[3] [4] 위키데이터
ETS 전위 변이체 1은 인체 내 에서 ETV1 [5] [6] 단백질 이다.
레퍼런스 추가 정보 Monté D, Coutte L, Baert JL, Angeli I, Stéhelin D, de Launoit Y (Aug 1995). "Molecular characterization of the ets-related human transcription factor ER81". Oncogene . 11 (4): 771–9. PMID 7651741 . Jeon IS, Davis JN, Braun BS, Sublett JE, Roussel MF, Denny CT, Shapiro DN (Mar 1995). "A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1". Oncogene . 10 (6): 1229–34. PMID 7700648 . Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry . 236 (1): 107–13. doi :10.1006/abio.1996.0138 . PMID 8619474 . Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing" . Genome Research . 7 (4): 353–8. doi :10.1101/gr.7.4.353 . PMC 139146 PMID 9110174 . Carrère S, Verger A, Flourens A, Stehelin D, Duterque-Coquillaud M (Jun 1998). "Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains" . Oncogene . 16 (25): 3261–8. doi :10.1038/sj.onc.1201868 PMID 9681824 . Coutte L, Monté D, Imai K, Pouilly L, Dewitte F, Vidaud M, Adamski J, Baert JL, de Launoit Y (Nov 1999). "Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human" . Oncogene . 18 (46): 6278–86. doi :10.1038/sj.onc.1203020 PMID 10597226 . Janknecht R (Nov 2001). "Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2" . The Journal of Biological Chemistry . 276 (45): 41856–61. doi :10.1074/jbc.M106630200 PMID 11551945 . Wu J, Janknecht R (Nov 2002). "Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A" . The Journal of Biological Chemistry . 277 (45): 42669–79. doi :10.1074/jbc.M205501200 PMID 12213813 . Janknecht R (Feb 2003). "Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)". Oncogene . 22 (5): 746–55. doi :10.1038/sj.onc.1206185 . PMID 12569367 . S2CID 30183941 . Goel A, Janknecht R (Sep 2003). "Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu" . Molecular and Cellular Biology . 23 (17): 6243–54. doi :10.1128/MCB.23.17.6243-6254.2003 . PMC 180970 PMID 12917345 . Dowdy SC, Mariani A, Janknecht R (Nov 2003). "HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81" . The Journal of Biological Chemistry . 278 (45): 44377–84. doi :10.1074/jbc.M307202200 PMID 12947087 . Goel A, Janknecht R (Apr 2004). "Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu" . The Journal of Biological Chemistry . 279 (15): 14909–16. doi :10.1074/jbc.M400036200 PMID 14747462 . Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (Jun 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology . 22 (6): 707–16. doi :10.1038/nbt971 . PMID 15146197 . S2CID 27764390 . Gocke CB, Yu H, Kang J (Feb 2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates" . The Journal of Biological Chemistry . 280 (6): 5004–12. doi :10.1074/jbc.M411718200 PMID 15561718 .
외부 링크
(1) 기본 도메인
(1.1 ) 베이직 류신 지퍼(bZIP )(1.2) 기본나선-루프-나선 (bHLH )
그룹 A 그룹 B 그룹 C bHLH-PAS 그룹 D 그룹 E 그룹 F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) 기본나선경간나선(bHSH)
(2.1) 핵수용체 (CYS4 )
서브패밀리 1 서브패밀리 2 서브 패밀리 3 서브패밀리 4 서브패밀리 5 서브패밀리 6 서브패밀리 0
(2.2) 기타 CY4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) 교대 조성 (2.6) WRKY